主要
成果和奖惩情况
| 发表论文：
1. An Tai, Li Shu, Pan Wei, Tien Po, Zhong Bo, Shu Hong-Bing, Wu Shuwen*. DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation. PLoS Pathogens. 2015 Sep 25;11(9):e1005179. (IF: 9.1)；
2. Xin Han, Ningyuan Sun, Haoming Wu, Deyin Guo, Po Tien, Chune Dong, Shuwen Wu* and Hai-Bing Zhou* Identification and Structure-Activity Relationships of Diarylhydrazides as Novel Potent and Selective Human Enterovirus Inhibitors. Journal of Medicinal Chemistry. 2016 Feb 25. [Epub ahead of print].( IF:5.447)；
3. Tazeem,ab Xin Han,ab Qingjun Zhou,c Jingchen Wei,d Po Tien,a Guichun Yang,c Shuwen Wu*a and Chune Dong*b A facile one-pot multi-component synthesis of novel adamantine substituted imidazo[1,2-a]pyridine derivatives: identification and structure–activity relationship study of their anti-HIV-1 activity
RSC Advances 2016, 6, 95177-95188（IF:3.84）
4. Jiawei Pan, Xin Han, Ningyuan Sun, Haoming Wu, Dandan Lin, Po Tien, Hai-Bing Zhou* and Shuwen Wu* Synthesis of N-benzyl-N-phenylthiophene-2-carboxamide analogues as a novel class of enterovirus 71 inhibitors RSC Advances .2015,5, 55100-55108.（IF：3.84）；
5. Xin Han, Haoming Wu, Chune Dong, Po Tien, Wei Xie, Shuwen Wu* and Hai-Bing Zhou*. Halolactones are potent HIV-1 non-nucleoside reverse transcriptase inhibitors .RSC Advances. 2015,5, 10005-10013.（IF:3.84）
6. Han X, Wu H, Wang W, Dong C, Tien P, Wu S*, Zhou HB*. Synthesis and SARs of indole-basedα-amino acids as potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Organic & Biomolecular Chemistry. 2014 Nov 7;12(41):8308-17.（IF：3.696）；
7. Wu S, Huang J, Gazzarrini S, He S, Chen L, Li J, Xing L, Li C, Chen L, Neochoritis CG, Liao GP, Zhou H, Dömling A, Moroni A, Wang W. Isocyanides as Influenza A Virus Subtype H5N1 Wild-Type M2 Channel Inhibitors. ChemMedChem. 2015 Nov;10(11):1837-45.（IF：2.968）
基金项目：
主持国家自然科学青年基金一项； 博士后基金二等资助一项，博士后特别资助一项，获批发明专利两项。
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